Year : 2016 | Volume : 4 | Issue : 2 | Page : 114 - 117  

Original Articles
Clinical behaviour of ocular surface squamous neoplasia (OSSN) in HIV positive patients

Clinical behaviour of ocular surface squamous neoplasia (OSSN) in HIV positive patients

  1. Padmavathi 1, D. Padma Prabha 2, Mohd. Ather 3, T. Kavitha 4, M. Padma 5

1, 2 & 5 Assistant professor of Ophthalmology, Sarojini Devi Eye Hospital, Osmania Medical College, Hyderabad

3 Professor I/C of Ophthalmology, Gandhi Medical College, Hyderabad

4 Assistant Professor of Pathology, Osmania Medical College, Hyderabad

Corresponding Author:

Dr. P. Padmavathi



Background: A lot of Ocular Surface Squamous Neoplasia(OSSN) may go unnoticed as they are asymptomatic and usually slow-growing. The prevalence of OSSN is more in tropical region and varies from 12 cases /million/ year in Uganda to 0.3 cases / million/ year in United States of America, possibly related to sunlight exposure. Objective: To study the clinical behaviour of Ocular Surface squamous neoplasia (OSSN) in HIV positive patients. Methods: This is a retrospective study done at the department of the oculoplastics and orbital diseases, Sarojini Devi Eye Hospital Hyderabad over a period of three years from February 2012 to January 2015. 26 cases of HIV positive patients with OSSN were included in the study and non HIV cases were excluded. Results: In our study of 26 cases 17 were males and 9 were females and average age of presentation was 34 years 10 to 15 years younger than non HIV cases. Histopathologically 18 cases were squamous cell carcinoma, 5 cases were carcinoma in situ and 3 cases were with moderate to severe dysplasia. Recurrence was seen in 8 cases (32.1%). Conclusion: OSSN presents at a younger age in HIV positive patients with aggressive behaviour clinically and histopathologically with more chances of recurrence.

Keywords: OSSN; HIV association; Clinical profile; Recurrence


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