Year : 2019 | Volume : 7 | Issue : 1 | Page : 11 - 15  

Original Articles
Correlation between clinical symptoms and forced expiratory volume in one second (FEV1) in patients of chronic obstructive pulmonary disease and asthma

Vinay Kumar1, K. Raj Kumar2, K. Sai Samrat 3*

 1Professor & HOD, 2 Associate professor, 3 Junior Resident, Department of Pulmonary Medicine, Chalmeda Anand Rao Institute of Medical Sciences,  Karimnagar, Telangana, India.

*Corresponding Author:



Background: Chronic obstructive pulmonary disease and Bronchial Asthma are the major causes of pulmonary disability. These diseases are characterized by airway obstruction. However, there are many differences between the two diseases with respect to their pathogenesis, pathophysiology, response to therapy and prognosis

Objective: To study the correlation between Clinical symptoms and Forced Expiratory Volume in first second (FEV1) in patients of Chronic obstructive pulmonary disease and Bronchial asthma.

Methods: 50 patients with a diagnosis of COPD and 50 patients of Bronchial asthma attending the outpatient department or admitted in the wards/ICU of Chalmeda Anand Rao Institute of Medical Sciences were examined and data collected on a pretested proforma.

Results: In Bronchial asthma, patients mean age was 33.3 ± 14.1 and majority (57%) were males. Mean FEV1 pre bronchodilator was 1.97±0.82 litre, Mean FEV1 post bronchodilator was 2.54 ± 0.86 litres.     In COPD patients, mean age was 64 ± 6.5 years and 87% were males. Mean FEV1 pre bronchodilator was 1.15 ±0.47 litres and mean FEV1 post bronchodilator was 1.24 ± 0.47 litres.

Conclusion: In Bronchial asthma, there was a trend towards significance between subjective wheeze & FEV1, but there was no statistically significant relation between total symptom score and FEV1.  In COPD patients, the single symptom approaching significant correlation with FEV1 was dyspnea.

Key words: Chronic obstructive pulmonary disease (COPD), Bronchial asthma, Spirometry, FEV1.


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