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ORIGINAL ARTICLE
Year : 2021  |  Volume : 9  |  Issue : 4  |  Page : 151-156

Clinical profile of dengue and its effect of on biochemical parameters: A hospital-based cross-sectional study


Department of Entomology, Greater Hyderabad Municipal Corporation, Hyderabad, Telangana, India

Correspondence Address:
Dr. Rambabu Ayyadevara
10-3-146, Flat No: G2, Sai Amrutha Nilayam Apts, Back Side of Busdepot, Mamilagudem, Khammam - 507 001, Telangana
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/mjhs.mjhs_31_21

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Background: Dengue affects the overall biochemical parameters and these characteristics can be utilized to monitor the progress of the patients. Hence, more and more studies are required to throw light on how these parameters differ in three different forms of dengue, i.e., dengue fever (DF), dengue hemorrhagic fever (DHF), and dengue shock syndrome (DSS). Hence, the present study was carried out. Objective: The objective of the study was to study the clinical profile of patients with dengue and to study the biochemical parameters in these three forms of the dengue. Methods: Hospital-based cross-sectional study was carried out among forty cases of dengue. In all these cases, various biochemical tests were carried out and correlated with three forms of dengue. These parameters were compared in three groups of patients, i.e. DF, DHF, and DSS. Results: Majority (70%) were having classical DF. The most common clinical feature in all three types of dengue was fever. Creatinine, blood urea, total bilirubin, and direct bilirubin mean values were significantly higher in DSS cases compared to DF cases (P < 0.05). Alkaline phosphate was significantly increased, and total proteins were significantly reduced in DSS cases (P < 0.05). Packed cell volume, total white blood cell, and erythrocyte sedimentation rate were significantly more in DHF cases compared to other two groups. The mean platelet values were significantly reduced in DSS group compared to other two groups (P < 0.05). Conclusion: DF is the most common presentation of dengue. DSS and DHF affect the biochemical parameters significantly and can be used to monitor the progress during the management of cases.


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